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NSABP Foundation phase 3 prospective nsabp b-40 trial
Phase 3 Prospective Nsabp B 40 Trial, supplied by NSABP Foundation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/nsabp-40/phase+3+prospective+nsabp+b+40+trial/pmc11526682-187-26-29
Average 90 stars, based on 1 article reviews
phase 3 prospective nsabp b-40 trial - by Bioz Stars, 2026-10
90/100 stars

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Related Articles

Adjuvant:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Comparison:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Selection:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Biomarker Discovery:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Sequencing:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Staining:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

In Situ:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Polymerase Chain Reaction:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Irradiation:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Infection:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Imaging:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Control:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).

Magnetic Resonance Imaging:

Article Title: Capecitabine for hormone receptor-positive versus hormone receptor-negative breast cancer
Article Snippet: Background Retrospective analyses suggest that capecitabine may carry superior activity in hormone receptor-positive relative to hormone receptornegative metastatic breast cancer.. This review examined the veracity of that finding and explored whether this diIerential activity extends to early breast cancer.. Objectives To assess eIects of chemotherapy regimens containing capecitabine compared with regimens not containing capecitabine for women with hormone receptor-positive versus hormone receptor-negative breast cancer across the three major treatment scenarios: neoadjuvant, adjuvant, metastatic.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: NSABP‐40 {published data only} Bear HD, Tang G, Rastogi P, Geyer CE, Andre R, Atkins JN, et al.

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Six included studies (31 records) referred to six treatment comparisons in the neoadjuvant setting ( ABCSG‐24 ; GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ; Zhang 2016 ).

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Given unblinded study, high risk due to difference in toxicity profile Incomplete outcome data (attrition bias) All outcomes Low risk Adequate reporting of pre‐specified primary and secondary endpoints; all randomised patients included in ITT analysis Selective reporting (reporting bias) Low risk Adequate reporting of pre‐specified primary and secondary endpoints Other bias Low risk No other sources of bias detected Open in a separate window NSABP‐40 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: The six neoadjuvant RCTs included were NSABP‐40 , ABCSG‐24 , GeparQuattro , Lee 2008 , Zhang 2016 , and Yoo 2015 .

Article Title: Capecitabine for hormone receptor‐positive versus hormone receptor‐negative breast cancer
Article Snippet: Open in a separate window 9.4 Analysis Comparison 9: Neoadjuvant: addition of capecitabine vs standard chemotherapy, Outcome 4: PCR triple‐negative (breast and nodes). . Disease‐free survival Four studies reported data on disease‐free survival (DFS) ( GeparQuattro ; Lee 2008 ; NSABP‐40 ; Yoo 2015 ).



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